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Taking vitamin D (or other essential nutrients) to alter your immunity must occur before exposure to any potential pathogen. It has no value as a treatment. The importance of yearly testing to maintain a serum level of
25(OH)D3 within 40-60 ng/ml cannot be stressed enough. Higher or lower levels of serum D are NOT beneficial to long term health.

Also important- listening to your body. To get help look here- Caution- Living Systems are Complex Systems  and do download and read Courtney Chandrea's book Re-rooting: A Landmark Map to the Wild Soul.

I am giving my book, Naked at Noon, Understanding Sunlight and Vitamin D (download only) without charge to anyone who would like to read it. Please honor the copyright and do NOT copy and paste anywhere. LARGE pdf so will NOT work on your cell phone, you will need a computer, ipad or kindle/tablet.

The book does NOT tell you how to 'dose' vitamin D. The only way to know how much D you have and how much D you need is through testing. https://omegaquant.com has an at home test kit for $49. Once you test pick a reasonable dose of vitamin D3 and retest after not more than 3 months to make sure your dose is working. Always test yearly. There is NOT a D-Dose but a human who requires a certain amount of D from sun or supplement to achieve a healthy serum level of 25(OH)D3. You cannot know, your doctor cannot know without testing. In addition, high doses of vitamin D not balanced with Vitamin A (not beta-carotene) will imbalance your immune system. If you need help fill out my new client form.

J Investig Med. 2011 Aug; 59(6): 881–886. doi:10.231/JIM.0b013e31821b8755
Vitamin D and the Immune System Cynthia Aranow, MD, Investigator
It is now clear that vitamin D has important roles in addition to its classic effects on calcium and bone homeostasis. As the vitamin D receptor is expressed on immune cells (B cells, T cells and antigen presenting cells) and these immunologic cells are all are capable of synthesizing the active vitamin D metabolite, vitamin D has the capability of acting in an autocrine manner in a local immunologic milieu. Vitamin D can modulate the innate and adaptive immune responses. Deficiency in vitamin D is associated with increased autoimmunity as well as an increased susceptibility to infection.

Nutrients. 2015 Apr; 7(4): 3011–3021.
Vitamin D and 1,25(OH)2D Regulation of T cells
Margherita T. Cantorna,1,2,* Lindsay Snyder,1 Yang-Ding Lin,1 and Linlin Yang1
Vitamin D regulates more than 2000 genes. It is important, but NOT a treatment. You need it before you get sick.

What makes taking and TESTING D essential is that it may take months to raise or lower serum D to within the ideal range and the required dose to reach and maintain that level is different for different individuals. Only by regular testing can you confirm YOUR ideal dose of sunlight and/or vitamin D AND if you change your source of D (supplement) you will need to retest every few months to make sure the new supplement is equivalent to the old. D is fat soluble, must be taken with food/fat and absorbs differently based on soft gel, capsule, type of D, irradiated ergosterol or fish oil derived.

Living systems are complex systems. It is NOT like having a headache taking an aspirin. You must plan ahead. Find out what works for you on a daily basis and maintain your base with all essential nutrients from foods and if needed supplements. Always food first but for vitamin D supplements are often needed. We do not all live near the equator, nor can we safely sun mid-day in many locations. Skin color makes a difference. The range 40-60 ng/ml for 25(OH)D3 has been set by many thousands of persons tested in many years of studies showing within that range, neither higher nor lower, all basic markers of long term health and freedom from disease were optimal.

It is true some may be healthy with slightly lower or higher serum D but most will not. Find your dose, take it daily along with good food, exercise and FAITH NOT FEAR and be prepared for whatever may come with peace of mind and body.

In the December 2012 issue of Cell Metabolism researchers report elevated fasting insulin occurs long before the presence of Metabolic Syndrome. Elevated fasting insulin appears up to five years before any other symptoms and that is important because

iomed Res Int. 2013;2013:921348. doi: 10.1155/2013/921348. Epub 2013 Jan 14. Possible role of hyperinsulinemia and insulin resistance in lower vitamin D levels in overweight and obese patients.
De Pergola G, Nitti A, Bartolomeo N, Gesuita A, Giagulli VA, Triggiani V, Guastamacchia E, Silvestris F.Source
Clinical Nutrition Unit, Department of Biomedical Sciences and Human Oncology, Section of Clinical Oncology, School of Medicine, University of Bari, Policlinico, Piazza Giulio Cesare 11, 70124 Bari, Italy. gdepergola@libero.it
A cohort of 66 healthy overweight and obese patients, 53 women and 13 men were examined. Waist circumference and fasting 25(OH)D, insulin, glucose, lipid (cholesterol, HDL cholesterol, and triglyceride), C-reactive protein (CRP), and complement 3 (C3), and 4 (C4) serum concentrations were measured. Insulin resistance was assessed by the homeostasis model assessment (HOMA
25(OH)D levels showed a significant negative correlation with BMI (P < 0.01), waist circumference (P < 0.05), fasting insulin (P < 0.01), HOMA(IR) (P < 0.01), triglycerides (P < 0.01), CRP (P < 0.01), C3 (P < 0.05), and C4 (P < 0.05). Multiple regression analyses were performed with 25(OH)D as the dependent variable and BMI (or waist circumferences), fasting insulin (or HOMA(IR)), triglycerides, and CRP (or C3 or C4) as independent variables. Only insulin or HOMA(IR) maintained a significant independent association with 25(OH)D levels, whereas vitamin D did not maintain a significant independent association with CRP or C3 or C4 concentrations.
The present study, performed in overweight and obese subjects, shows that 25(OH)D levels are negatively associated with inflammatory parameters such as CRP and C3 and C4 levels, but not independently of BMI, body fat distribution, insulin levels, or insulin resistance. Our results suggest that hyperinsulinemia and/or insulin resistance are directly responsible for decrease of 25(OH)D levels in obesity.

Low vitamin D is strongly associated with Metabolic Syndrome but if elevated fasting insulin is causing the problem taking vitamin D won't fix it. Lower fasting insulin first =<6 uUnit/ml. Then test your vitamin D. Easiest way to lower fasting insulin is 8/16 Intermittent Fasting. To test fasting insulin click here.

Our genes may increase or decrease our need for vitamin D.  23andme.com offers DNA testing which will provide raw genetic data that, if analyzed will tell you how your VDR (vitamin D receptor) genes are functioning. Less performing genes will require higher doses of D to maintain D status. For more information about VDR genes look here. Testing is the only way to make sure you 'have enough' vitamin D and testing D once or twice a year will assure you of sufficiency without genetic testing.

Another cause of low levels of 25(OH)D even when taking significant amounts of vitamin D may be insufficient vitamin C. It is vitamin C that supports conversion (hydroxylation) of D3 into 25(OH)D and 1,25(OH)2D. Do sign up for the newsletter (below). The July 4, 2011 issue is about vitamin C and includes information on the role of vitamin C and osteoporosis, vitamin C is the critical factor to both prevent and reverse osteoporosis. Vitamin D and calcium neither prevent nor cure osteoporosis, though adequate D and calcium are essential for healthy bones.

New information regarding the genomic functions of vitamin C (ascorbate) and ascorbate interaction with and importance to vitamin D metabolism and function has been added to all my information, the book, workbook and sun packet. All references are updated. This is an important update of the Preliminary Report Sunlight package, the book and the workbook.

April 24, 2011- published April 19, 2011 in the British Medical Journal a meta-analysis of 36,282 postmenopausal women given calcium or calcium with vitamin D found higher incidence (slight but there nonetheless) of MI (myocardial infarction) with or without stroke. The researchers could not determine the exact cause but suggest the acute rise of calcium after supplementation may be a problem as both high and low dose calcium with or without D were implicated. From the study-

"...This would be consistent with the notion that the abrupt change in plasma calcium concentration after supplement ingestion causes the adverse effect, rather than it being related to the total calcium load ingested."

Please make sure, if you do take calcium, as suggested in the Workbook and Preliminary Report, take small amounts throughout the day with food. Also consider that minerals are best in combination, not as singular elements, and consider that vitamin K2 MK7, minimum daily dose 1200 mcg of menaquinone-7, 5 mg of menaquinone-4 and not less than 1000 mcg vitamin K phyloquinone, is critical to the health to every cell in human body, bone, muscle, skin, teeth, nerve, every cell requires sufficient levels of MK-4, MK-7 and vitamin K1. No other vitamin shows as much potential for anti-aging and for regeneration. More information will be found on vitamin K, all forms, in both the workbook and report. Vitamin Ks only work if you have adequate docosahexaenoic acid, pre-formed vitamin A and adequate vitamin D. Adequate always means 'enough but not too much'.

April 2011 A phone call worth posting. A women working with a physician tested 25(OH)D at 36 ng/ml (optimal 40-60 ng/ml) about 3-4 months ago. Her physician told her to take 20,000 IU vitamin D daily. This week she tested 157 ng/ml. Her physician said lots of her patients tested that high and there is no problem and that she should reduce her dose to 5,000 IU. The woman asked my advice. First I suggested she find another physician. Then I suggested she stop all D and sunlight exposure, and lower her calcium intake, until her 25(OH)D dropped below 60 ng/ml. It took more than 6 months for her levels to reach ideal, 40-60 ng/ml.

If this is your physician or if your physician is like-minded I suggest you, also, get another physician. As I have stated here and in my book, there are consequences when ingesting excess vitamin D, though among D enthusiasts this idea is not yet accepted. One possible consequence is demineralization of bone and/or mineralization of soft tissues. This may happen without any unusual blood work, serum calcium remaining normal. It has been documented by Adams, Kummerow, and Kartha. There are other possible consequences.

The partial article below may be found in full here. What it demonstrates is that D and minerals do not work alone. Just getting enough D and/or calcium is NOT an answer.

Vitamin C protects, maintains healthy bone mass Dipali  Pathak
HOUSTON -- (May 11, 2010) -- Vitamin C, or ascorbate, plays an important role in maintaining bone mass - promoting the balance between old bone resorption and new bone formation, said researchers from Baylor College of Medicine and Lexicon Pharmaceuticals in a report that appears online in the Journal of Biological Chemistry.

"The assumption is that everyone gets enough vitamin C in their diet," said Dr. Kenneth Gabbay, professor of pediatrics - molecular diabetes and metabolism at BCM. "However,
multiple studies of large groups of people show that higher intakes of vitamin C are associated with higher bone mass and lower fracture rates. Our study shows that vitamin C or ascorbate is critical to maintaining the homeostasis necessary for healthy bone mass."...

...Gabbay and his colleagues built on the fact that mice can actually synthesize vitamin C, an ability that is lacking in humans. They identified two enzymes critical to this process by providing the building material for vitamin C - aldehyde reductase and aldose reductase. Aldehyde reductase is responsible for 85 percent of vitamin C production and aldose reductase, the remaining 15 percent. Mice bred to lack both enzymes cannot make any vitamin C and develop scurvy, a condition that affects many organ systems including bone.

However, if mice lack only aldehyde reductase, they and their skeletons develop and grow normally on the 15 percent ascorbate or vitamin X generated through aldose reductase until they face a stressor that requires more vitamin C, such as pregnancy or the loss of sex hormones that accompany menopause and aging.

"Then they fall off a cliff and develop early profound osteoporosis," said Gabbay.

His studies (in mice) show that
ascorbate or vitamin C both suppresses osteoclasts, which promote bone resorption, and stimulates the development of osteoblasts that make new bone, thus enhancing new bone formation. The constant renewal of bone is crucial to healthy bone architecture.

Many treatments for osteoporosis, including bisphosphonates such as Fosamax and Actonel, suppress the function of osteoclasts, and hence blocks bone resorption and mechanisms of bone repair. Unfortunately, these treatments do not stimulate osteoblast formation and new bone is not made.
Many anti-oxidants such as resveratrol (found in red wine) and pycnogenol do the same thing. Only vitamin C affects both sides of the equation - osteoclast suppression and osteoblast development, said Gabbay.

..Most experts recommend vitamin D, calcium, exercise and bisphosphonates to keep bones healthy, said Gabbay. "Vitamin C is never mentioned, whereas it's likely an equally important element for maintaining strong healthy bones" he said. "Our studies necessitate formal studies in patients to evaluate the usefulness of vitamin C therapy in susceptible populations."

Nov. 12, 2009 I read in my inbox that having enough vitamin D absolutely prevents and reverses breast cancer, really. It doesn't. Having adequate vitamin D is healthier overall than not having adequate vitamin D but many persons with low D don't get cancer and some persons with adequate D still get cancer. Health is about the living body, NOT individual nutrients.

In many of the studies the critical point for all outcomes lowered risk is having more than 30 ng/ml which makes sense as optimal remains 40-60 ng/ml. When you read articles or research you have to understand risk . Taking a particular supplement or sunning or any other treatment to prevent anything carries benefits and risks. Having an excellent diet and making sure you get enough but not too much D will LOWER YOUR ODDS but life being what it is, a complex living system, there are many factors known and unknown and no sure things .

I have had several clients over the years with more than adequate vitamin D (between 48-59 ng/ml) and breast cancer. And the studies regarding the reversal of breast cancer with vitamin D were about analogs (artificial molecules created in a lab) used on cancer cells not in actual women. I visited one site proposing such nonsense and read that the ideal amount of 25(OH)D is 60-80 ng/ml and again NO it is not. In our fast times we seem to misread the research and project miracles where they do not exist. I am saddened by the misuse of research and am at a loss to understand why this is occurring. We need vitamin D. When we have between 40-60 ng/ml we are healthier, maybe even happier, but it won t prevent or cure anything, clinically, except secondary hyperparathyroidism and rickets.

Vitamin D with or without calcium has not even been that great at preventing or reversing osteoporosis. There are just too many other things we need to be healthy to lump it all on this one thing . When will we give up the magic bullet? persons promoting high dose and high serum D for the prevention of cancer or any other specific disease really don t understand the human body or vitamin D. Do listen to them with caution, please. And it is true, really, too much D is as unhealthy as too little. Enthusiasm seems to blind us to logic and common sense.

The good news in 2022 is that we are closer than ever before to understanding the LIVING cells that make up a healthy body. Come back because in the next few months I will be posting an ongoing study showing we really can regenerate, without drugs, genetic engineering, stem cell therapy or exotic, expensive nutrients. The data is coming in that the missing elements for the planet and for our bodies reside in the planetary microbiome. Prepare for a bright future. If you would like to be notified when the information is posted send me an email.

Questions and Answers:

Question: Do I have to worry about not getting enough UV-B exposure (for Vitamin D), during the winter, since I live in Denver, which, obviously is 5,280 above sea level? I apologize for bothering you, but, I could not find this answer anywhere on the Internet. Obviously this answer will make a big difference on how much Vitamin D supplements I need to take.

Answer: Yes and No. Each 1,000 feet in elevation equals about 1 degree closer to the equator (from where you are) so Denver, latitude 39.46° at altitude 5,280 ft would have a similar UV-B to a location at 33-34°, not all that UV-B rich. Reflective snow in winter would make mid-day more intense but as to available D it just isn't t all that much because UV-B is less in winter in all locations more distant from the equator. Only locations 30° or closer to the equator have consistently intense UV-B. Whether using sunlight or supplements the only way to know how much you need is to record how much you get and test 25(OH)D.

Supplemental D or sun exposure should not be based on location because your need for D depends on much more than that; your skin color, your age, your sunning habits, your diet, your genes, your weather (clouds, fog and some urban pollution, aka urban ozone, block UV-B). The only way to know how much D you have and how much D or sun you need and if the supplemental D or sun, or tanning bed you are using is working is TESTING. TEST and RETEST, don t guess. Your HMO, your physician, lef.org or ZRT Labs provide you a means of monitoring your D. Use your resources.

Question: Since we cannot really live half of the year in the tropics, we thought about using UV lamps, but it is hard to know which type can reliably deliver the correct amount of UVB rays. Have you investigated specific brands etc? Unfortunately, there is not much help to be had from local doctors, as they usually have a deep prejudice against UV lamps instilled by dermatologists.

Answer: Wolff tanning beds (beds that use Wolff lights) may be used to replete vitamin D. These beds are often referred to as "20 minute" beds. The amount of UV-B is similar to summer sun BUT the danger is in staying too long. You make all the D you will make BEFORE your skin alters in any way, even the very lightest of pink . Tanning actually reduces the amount of D you are able to produce on your skin. Light skinned persons would need 7-10 minutes, maybe less, to produce significant amounts of D. A responsible proprietor and NEVER staying longer than you need are keys to safe use of tanning beds. Further instructions on safe use of beds may be found in the Sunlight packet below. A note of caution- any exposure to UV light lowers the amount of vitamin A and vitamin C in your skin .If you decide to use light to produce vitamin D consider how much extra A and C you need to keep your skin happy and healthy.

Question: ...have read (looked at) several articles on this subject. They give good descriptions of the beneficial effects. But so far, I have not seen (Yes, I m sure it is there, somewhere!) a listing of times considered advantageous. And yes, there are many factors. For instance, time of year, condition of the sky etc but the one I'm interested in is time for an average person, at a reasonable latitude, like 35 °, and importantly the % coverage of the sunlight recipient! If a person is nude they require less time than if one is in normal clothing and a person dressed like an Eskimo might as well stay inside. Can you give any benchmarks for a person such as me. And yes, I have another disadvantage, I m 86 years old!

Answer: Some researchers suggest a particular amount of sunlight is equivalent to a particular dose of D. I have been testing 25(OH)D in several hundreds of clients since 1999 and found no correlation of either D intake or sun exposure and 25(OH)D that was useful long term as a rule or guideline for others.

Aging skin produces significantly less D even when UV-B is present and there is the issue of excess sun exposure, level of vitamin A present in skin, level of cellular anti-oxidants including vitamin C, and the incidence of skin cancer. Life requires we balance benefit and risk of all our behaviors.

At 38° north a very light skinned person might need 10-12 minutes per side, mostly naked, between 10AM and 2pM, to raise D to between 50-60 ng/ml. By December 25(OH)D may drop below 40 ng/ml. If the location was in a city (with city haze) vitamin D production might be much less.

Nude does not correlate with time at all. You make as much D as you will make just prior to erythema (pinkness or the equivalent) which might be 7 minutes in very light skin and as much as 120 minutes in very dark skin (which also may burn from excess exposure but you won t see it). Sunning longer will not produce more. You have just so many genetically pre-determined "vitamin D factories" per cm of skin, some parts of the body having more factories than other parts. More skin will produce more D but again, this is a genetically determined variable with wide variations in amount . In addition to amount of skin exposed UV-B intensity, skin color, skin age and your genes all alter outcome.

A client who took no D, lives on the East Coast and has little sun exposure, tested with moderately HIGH levels of 25(OH)D. For her supplementation or more sun exposure would be excessive. Sunning requires first that significant UV-B is present which at 35° would be (depending on altitude and city/country) perhaps April 15-Sept 15 between 10AM and 2pM. The closer to noon the higher the UV-B.

Repeated testing of whatever method you choose to use, sun or supplements or a mix of both, will show you if your choice is effective. If it is not, make a different choice.

Question: Whenever I try to take D I experience ... (allergic reaction, depression, digestive distress, weakness, sleepiness, muscle or nerve reaction, or other unpleasant reaction). How do I get/take D?

Answer: You may need someone to help you determine all your nutritional needs, not just vitamin D. Things work together in our bodies. We need protein, high potassium foods (fruits/vegetables), small amounts of vitamins and minerals and trace elements to make things work right . Just adding one or two things may make others work less well. We are complex living systems. Consider a consultation. Read the http://krispin.com website. As the clinical studies show, having high amounts of vitamin D without A may create a relative functional vitamin A deficiency as having high amounts of vitamin A may create a relative functional vitamin D deficiency.

Supplement companies are selling vitamin D in doses from 400 IU to as much as 50,000 IU. Supplement companies periodically send newsletters continuing to report the benefits of vitamin D and harmful effects of having too little D. One might assume buying and taking one of these supplements will make sure you are sufficient in vitamin D. When I began researching vitamin D for my book I thought I would find a wonderful substance that prevented and perhaps even cured many diseases and that the subject would be simply, wow, it s great, make sure to get lots. That was in 1999.

Regardless of how many new papers are published the facts remain the same. Every person absorbs and/or produces vitamin D in varying amounts. One person may simply expose arms and legs several times a week and have and maintain adequate levels of D, others may take a supplement of 4,000 IU daily and for various reasons not increase their 25(OH)D at all. And again, others may simply increase calcium intake and their 25(OH)D will rise with no supplemental D. I cover this in detail in the Sunlight packet/Preliminary Report and further discuss why this may happen in the book/manuscript.

I made the decision to provide these resources because people need to know. I literally print out the items at the time they are ordered because it allows me to make changes along the way as I find a better way to state what is true. It is not my truth. It is not conjecture or opinion. The facts presented are a distillation of ongoing considered study of the literature from the first discovery of vitamin D to the present day, and hands on experience working with people, sunlight and vitamin D over the past 21 years. I consider this to be a part of my service.

Some people need more D, from sunlight and/or supplements. Some people don't. Some people need more than other people because of many and varied reasons. The information in the packet and the manuscript is as factual (with references) today as when they were written and if updating is needed it is (and has been) done.

My concern about excess D supplementation continues because the marker of excess D being used currently (high serum calcium or urinary calcium or both) is not the only validated marker/side-effect of excess D. Excess serum cholecalciferol (D3, what you make from sun or take in a supplement) and/or excess 25(OH)D may interfere with the actions of 1,25(OH)2D, the so-called active hormone D, without changing serum or urinary calcium. As 1,25(OH)2D has (so far) 50 known cellular targets (according to Walter Stumpf, PhD, personal communication) though only 30 are currently recognized, most of them not related to bone, making sure you get enough but not too much is important. ANY possible benefits of over-enthusiastic sunning or supplementing which increase 25(OH)D beyond 60 ng/ml are not supported by any research studies. Taking 5,000 IU or 10,000 IU daily for some period of time may give you the test results you want BUT continued use of that same dose may continue to raise your D beyond optimal limits. TEST, make sure you really are getting and using what you take, enough and not too much.

If you want the story request the book which covers the history of D and sunlight and the what and why . If you need to know how to monitor and maintain optimal vitamin D safely, request the Report with protocols.

The book, Naked at Noon, does not contain detailed instructions on how to maximize vitamin D safely. For all vitamin D enthusiasts- please do not take D in amounts larger than 2,000 IU daily from all sources without clinical testing, physician guidance, or cautious personal monitoring if a physician is unavailable. Read the excerpts from the book. Some may benefit from 2,000 IU or more daily BUT it is important to KNOW, not guess.

Harm can occur from excess D as well as insufficiency. Taking D when it is not needed is potentially dangerous no matter what form of D you may be taking. Do not self treat without regularly monitoring your levels of 25(OH)D and seek help if you aren't t sure how to do this..

Various websites and experts are enthusiastic about vitamin D and state high doses of vitamin D, doses ranging from 2,000-10,000 IU or more, are safe. A primary focus of my book is a review of research showing studies being cited as the basis for claiming high doses of vitamin D are necessary and safe were faulty when they were first published. High doses of D may be absolutely necessary for some but for others the same dose would be excessive in the short or long term.

The conclusions drawn by safe vitamin D proponents (including some of the researchers themselves) often overlook major flaws in the studies. To mention just one of the flaws, few studies have been done using high dose vitamin D for longer than 6 months. A recent study with children lasting a year found several of the participants with excess levels of vitamin D. D toxicity (like vitamin A toxicity) may take a year, two years, or longer to develop, putting the compliant patient/user at risk.

Another overlooked problem is the interaction between calcium and vitamin D. Taken together there is a strong synergistic effect and less amounts of both substances are needed. As testing is done without correction for calcium intake conclusions are again, problematic. High doses of D when calcium sources are low have a different outcome than when D and calcium are used in combination. The US diet is relatively high is calcium (depending of course on who, when, where) and for many (not all) calcium lowers the relative need for vitamin D.

I have seen the outcomes, having begun working with high dose D in 1999. The book clearly describes the problems facing any policy of food supplementation or long term high dose D supplementation.

I am enthusiastic about safe use of sunlight and vitamin D. Having enough D makes life better. I know from experience supplementing D can be problematic.

Some supplement users absorb poorly, some combine supplements with sunlight for rapid excess, some use supplements that just don t seem to work. My personal preference is the safe use of sunlight to get D but I know that for many this may be impossible. It is a new world out there. We have moved from ancestral sources and have no way to recreate these sources in our new locations. Whether using sunlight or supplements, testing makes sure you are getting enough and not too much.

For an overview of why caution is advised do read the book excerpts, and Caution- Living Systems are Complex Systems.

I would say from a review of the research and from personal and professional experience most benefit from extra D, especially D from sunlight, but we are all individuals and what is right for one may not be right for another.

Enthusiastic promoters of natural vitamin D or cod liver oil suggest that, as it is natural, it is safe in high amounts. Some use references to prove their claims. Clinical data strongly contradicts any belief that high doses of vitamin D, whatever the source, are safe. It is true, however, getting excess A and D combined, as is possible with excessive cod liver oil intake, is safer than excess D or excess A alone. Vitamin A is protective when excess D is present and D protects from excess A, BUT having the right amount, neither excess or insufficiency of either makes more sense.

 There have been a number of cases reported to me of vitamin D excess with debilitating results, including tetany, depression, and/or significant bone loss. None of these persons experienced the clinical definition of hypervitaminosis D but these are unhealthy side-effects nonetheless. Monitor your D.

For the past number of years clinicians, physicians, national media, and the National Institute of Health have been warning Americans to stay out of the sun. The purpose of this warning is intended to prevent melanoma, a serious form of skin cancer. In spite of the ever-increasing use of sunscreens and intentional reduction of sun exposure, incidence of this cancer continues to rise. There is evidence that the advice to avoid sunlight may be contributing to the increased incidence of melanoma. One possible reason for this may be issues relating to genetics and extended exposure to UV-A light. When sunscreen is used sun burning is reduced or eliminated and the sunscreen user s time in the sun is extended. While UV-A is not as strong as UV-B it does cause damage over time and most sunscreens either do not block or poorly block UV-A no matter what the SPF may be. Whatever the cause, the expected reduction in skin cancer with sunscreen use has not occurred.

One of the known protectors of skin cells from pre-cancerous changes is vitamin D and your skin actually contains the enzyme that converts sunlight D into active 1,25(OH)2D, calcitriol. For most Americans the primary source of vitamin D is sunlight. UV-B, the only band of light producing vitamin D, is significantly present only midday from late spring to early fall in most of the U.S., the exact time we are advised to avoid sunlight. UV-B is blocked by sunscreen. We have an international disaster in progress due to a misunderstanding of the nature of and need for UV-B and vitamin D.

A blood test for 25(OH)D, 25-hydroxyvitamin D, is the only way to tell if you have or are taking the correct amount of vitamin D, need to take any D, or if your sun habits are sufficient. Too little vitamin D contributes to many degenerative diseases and other epigenetic changes but excess vitamin D is equally undesirable. Because of the varied ethnicities, latitudes and lifestyles in the United States (and most of Europe and Asia too) the only way to safely use supplemental vitamin D is test, test and retest. Click on the Vitamin D Testing link for a relatively inexpensive way to monitor your D.

Low D needs to be corrected, carefully. Moderately high levels of 25(OH)D, greater than 70 ng/ml (175 nmol/l) have been associated with bone loss, heart disease, and other soft tissue calcification. When chronic intake of excessive amounts of vitamin D raise serum 25(OH)D further, irreversible damage may occur. The optimal range of vitamin D is 40-60 ng/ml (100-150 nmol/l).

In locations greater than 30° latitude, north or south, values are naturally higher at the end of summer and early fall and lower in winter and spring. There is no evidence values higher than 60 ng/ml provide any added benefit.

 Reasonably priced testing is available for anyone in the US from the Life Extension Foundation. ZRT Labs is more expensive but may be an alternative choice for some and as the test is done at home from a small blood drop may be preferable for infants and children. Unfortunately the ZRT test is not available in California or New York.

Click on the little suns to reach the test ordering pages (let me know if any links are broken).

 SunAt LEF.org the test is $47 for LEF members and $63 for non-members. Test results are provided directly to you through the Foundation. Testing sites are easily accessible in most states. I am not a member nor in any way affiliated with Life Extension, nor do I promote their products. I do support reasonably priced testing of vitamin D. Life Extension also offers a reasonably priced fasting insulin test.

SunOmegaQuant offers home testing AND they also test for omega-3/omega-6 ratio. Good site, lots of info.

SunHome Health Blood Test provides a do-it-yourself at home blood spot kit. It is good for those that want to take control of their own testing or excellent if you need to test infants or children (no needles). The price is $60 for a blood spot kit that is accurate and requires just a few drops of blood. Unfortunately this test is state limited. Make sure you live in a state that allows self testing (not New York or California)

Do not supplement in amounts greater than 2,000 IU (total from all sources daily) unless you are testing regularly. You want to take the total daily amount that, when testing summer and winter, maintains the ideal 40-60 ng/ml. Minimum testing, if using supplements, should be not less than every six months the first two years and once a year every year thereafter. If you change your D supplement RETEST. Supplements are not equivalent. Insufficient serum D will impair your health. Excess intake of vitamin D may not show up as elevated 25(OH)D until as long as 2-3 years after starting a dose that was seemingly safe initially.

Less testing is needed if you use sunlight to raise your D. Typically end of summer and end of winter will give you a good idea of the success or failure of using sunlight as your primary source. Sunlight is a safe source for most persons in the US with the exception of light skinned persons living in Hawaii, Florida or other locations with elevated levels of UV-B. All skin types regularly exposed to UV light will have a higher need for dietary vitamins A and C which protect the skin..

If you have light skin and live in an area with high UV-B, sunning should be very limited. Combining sunlight and supplements may rapidly overload the D endocrine system in summer months.

If you regularly sun in summer and have skin types 1-3 it is possible no supplementation is needed during all or most of the year. You must test to KNOW. For darker skins the only US location likely to provide adequate sunlight is southern states and Hawaii. You must test by current supplement and sun exposure to determine your PERSNAL need and optimal supplement. Supplemental D may be a requirement for long term health. As response to supplementation is difficult to gauge, testing should be mandatory. Most HMOs will recognize the benefits of supporting optimal 25(OH)D. The Preliminary Report explains how to determine your need and how to use supplements and sunlight safely. A physician protocol is included with the Report to share with your doctor.

SunVitamin D, the kind you make on your skin, get in fortified milk, or take in a vitamin supplement, is not a vitamin. Vitamin D regulates more than 2000 genes. It is more appropriately classified as a pro-hormone. Not only is it a pro-hormone it is a sunlight derived pro-hormone. The active hormone D, calcitriol, 1-25(OH)D, controls calcium in vertebrates and invertebrates. Calcium controls innumerable processes in the human body including specific responses in muscles, bones and glands.  Calcitriol is a major player in genomic actions determining how our cells express themselves and regulating production of numerous substances including enzymes, hormones and neurotransmitters

** PLEASE DESCRIBE THIS IMAGE ** We all need sunlight and/or vitamin D. Clinical studies demonstrate our ability to produce/absorb/utilize sunlight and vitamin D is genetically variable. At the present time many persons world-wide suffer from D deficiency or insufficiency. Testing is the only way to know how much D you have and testing is the only way to monitor D supplementation. As actions of a pro-hormone are essential to health and life, guessing or assuming is not a wise way to determine optimal levels.

In northern California 80% of clients tested during winter months have serum vitamin D deficiency (less than 20 ng/ml) or insufficiency (20-32 ng/ml). This problem increases dramatically in persons living at latitudes more distant from the equator and in persons living in all US latitudes with darker skins. In Texas there has been an increase in the number of children with African or Hispanic heritage suffering from rickets. Even in sunny southern California vitamin D deficiency or insufficiency is prevalent in part due to avoidance of midday sunlight and/or the use of sunscreens which block vitamin D production .

Getting enough vitamin D, from sunlight or supplements, is important to health and longevity but too much supplemental D or sunlight can be disease producing. Too much, too little- the only way to know how much D you have and how much sunlight or D you need to maintain D sufficiency is to test.

Sun Every body needs sunlight and vitamin D. Deficiency or insufficiency has been associated with:

** PLEASE DESCRIBE THIS IMAGE ** To find out more about me please visit krispin.com and take a look around. This is my personal web site designed to provide basic information about me and about nutrition in the 21st century.

A revised edition of my nutrition workbook will be available mid-2022.  360+ pages including information on the microbiome (human and planetary), the benefits of high dose vitamin K, elevated fasting insulin (see below), omega-3 update, autophagy, Intermittent Fasting (IF), Time Restricted Feeding (TRF), MTHFR genes, telomeres, regeneration and your health, repairing dysfunctional mitochondria and the importance and culturing of ancestral anaerobic bacteria. Will post a notice here when it is ready or request to be notified when it is ready. info@krispin.com  

** PLEASE DESCRIBE THIS IMAGE ** NEED HELP NOW? I accept private clients internationally and work by phone, fax, mail and email. If you need personal help with any health issue, including support when undergoing traditional medical treatments email for the information packet. If you prefer call my home office, and leave your name, address, zip, phone number and email please. Speak slowly and clearly, spell any words likely to be mistaken on a message machine. I will e-mail (preferred and fast), fax, or mail you an information packet, no obligation, containing forms and a clear explanation of what I offer and what it costs. If you would like me to reveiw your information before making a decision to work will me include a note.

As stated I work by phone, fax, mail and email. I do not see clients in person. I do not sell ANY products though I do sell educational materials. I offer personal support and intensive education, to enable you to care for yourself (and for your family).

If you email or call with personal health information and questions and are not a client I will not be able to respond due to time constraints and other complicating legal and medical issues. Please request the Information packet which contains the information and forms needed to decide if you would like to consult with me to begin the process. The packet explains what I do and contains the forms needed to begin your consult. There is no obligation when requesting this information.  

Physicians with questions about vitamin D should request the Preliminary Report which contains a referenced physician's protocol and other materials. If questions remain after reviewing the report call me. 1-775-831-0292 physicians calling to discuss vitamin D issues re patients are welcomed. Have your questions prepared with detailed information on patient history. You may fax or email information and questions prior to your phone consult. You will be billed/invoiced for actual time used.

Krispin Sullivan, MS, CN
Voice 1-775-831-0292 (I am unable to answer personal health questions for non-clients. If you need help now email for the client forms and email or fax or mail them back with all information, including blood work, requested)
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